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Neuropathic pain: One of the potential clinical applications of NK cellsNeuropathic pain refers to pain directly caused by a certain injury or disease affecting the somatosensory system. Peripheral neuropathy causing pain may result...04-19
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Anti-aging health care -- one of clinical applications of NK cellsNK cells are the core participants in senescent cell immune surveillance. They increase with age, but their cytotoxicity and function continue to decline, which...04-08
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Research progress of universal cell therapyCAR-T cell therapy brings new hope to cancer patients with its unique targeted therapy. The 10 CAR-T drugs currently on the market are mainly autologous CAR-T c...04-08
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Metabolic challenges in CAR-T cell therapyCAR-T cell therapy has already shown great success in treating advanced hematologic malignancies. However, its efficacy in solid tumors has been unsatisfactory,...04-08
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A new strategy to enhance anti-tumor activity and persistence: reducing CAR-T cell methylation levelDNA methylation refers to the change of specific bases in the DNA sequence at the C-5 position of cytosine, the N-6 position of adenine and the chromium positio...04-08
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Shenzhen Cell Valley achieved a major breakthrough in CAR-NK preparation processIn response to the pain points in the early R&D and industrial production of CAR-NK cells, Shenzhen Cell Valley's core R&D team conducted long-term ...04-17
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Tumor cell immunotherapy -CAR-NK and CAR-M cell therapy一、What is CAR cell therapy T cells in the immune system can target and kill tumor cells, and the killing of tumor cells by T cells relies on the specific recog...04-17
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Knockout of CTLA-4 can improve the antitumor efficacy of CAR-T cellsOn September 29, 2023, Professor Carl June’s team published a research paper titled: Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorate...04-17
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Immune cell therapy pioneers in non-tumor fieldsIn recent years, CAR technology has developed rapidly and achieved breakthrough success in the treatment of hematological tumors. A number of CAR-T drugs have b...04-17
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Development, current situation and prospect of CAR-T cell therapy一、The development of CAR T cell therapy Cell and gene therapy (CGT) refers to a new therapeutic method that introduces exogenous genetic material into target c...04-17
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Application of safety switch in cell therapy一、Safety switch of cell therapy After autologous or allogeneic cell infusion, a large number of immune cells are activated and prolifed rapidly, resulting in e...04-17
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Advantages of retroviral vectors in CAR-NK cellsIn recent years, the success of CAR-T therapy has made people see the huge potential of immunotherapy, and has also become an important milestone in the history...04-17
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CRISPR/CAS9 technology in the field of cell therapy一、Introduction of CRISPR/Cas system CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat), first discovered in the late 1980s, is an unusual geneti...04-17
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Security research of virus vector一、Introduction Viral vectors are the most popular delivery methods for cell therapy and gene therapy. In cell and gene therapy, viral vectors that express anti...04-17
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Viral and non-viral vectors in CAR-T cell therapy一、Introduction At present, the construction methods of CAR-T cells used most mainly include three categories: viral vectors represented by retroviruses and len...04-17
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Viral vector, a key raw material for cell therapy一、Introduction Gene transfection is a key step in cell therapy, which refers to the delivery of plasmid DNA containing target genes to cells and their expressi...04-17
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Advances in CAR-T therapy for multiple myelomaMultiple myeloma (MM) is a malignant proliferative plasma cell tumor characterized by the abnormal accumulation of monoclonal plasma cells in the bone marrow an...04-17
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Cell therapy research status一、Overview of cell therapy Cell therapy refers to the transplantation or input of normal or bioengineered human cells into the patient, and the newly imported ...04-17
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CAR-T cell immunotherapy for acute myeloid leukemiaQuotation acute myeloid leukemia (AML) is a malignant tumor caused by the proliferation and differentiation of bone marrow hematopoietic stem cells. It is most...04-02